Our research addresses the design of complex sociotechnical systems, primarily in healthcare settings, using mixed methods approaches to support teams and improve outcomes. In healthcare, that means patient outcomes (e.g., patient safety, quality of care) as well as clinician outcomes (e.g., workload, burnout). Key components of our research approach include engaging frontline workers (patients and their family as well as various healthcare professionals) and utilizing mixed methods, i.e., both qualitative and quantitative, research designs.